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The Science Behind COVID-19

April 2020

The COVID-19 pandemic has swept the globe, yet many people still do not understand how it affects the body. This infographic shows the events that occur following SARS-CoV-2 infection.

As seen in:

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. You are free to copy and redistribute the material in any medium or format under the following terms:

 

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Translations

French

Français

Translated by Richard Ying

Romanian

Română

Translated by Andrei Cioban

Indonesian

Bahasa Indonesia

Translated by W. Kurniawan

Simplified Chinese

简体中文

Translated by Hu ChuanZhen

Afrikaans

Afrikaans

Translated by Graham Louw

Spanish

Español

Translated by Ronan's School and Luis Hume

Russian

русский

Alexander Golovkov and Dr. Jacob Mirkin

Portuguese

Português (Brasil)

Traditional Chinese

繁體中文

Adapted by Johnny SZE

Serbian

Srpski

Translated by Ivana Prokic

German

Deutsch

Translated by Ulrike Eberius

Arabic

عربى

Translated by Michael Refaat

Catalan (Spain)

Català

Translated by Joan-Carles Escolano

Italian

lo italiano

Translated by Simona Caporali

and Gilberto Genga

Turkish

Türkçe

Translated by Dr. Mustafa Özdoğan

Albaninan

Shqiptar

Translated by Aldi Pupuleku and HEDA

Ukrainian

Українська

Translated by Serhiy Chornoknyzhnyi

Xhosa

isiXhosa

Translated by Patience Zantsi​

References

  1. Belouzard, S., Chu, V. C., & Whittaker, G. R. (2009). Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites. Proceedings of the National Academy of Sciences, 106(14), 5871–5876. doi: 10.1073/pnas.0809524106

  2. Gates, B. (2020). Responding to Covid-19 — A Once-in-a-Century Pandemic? New England Journal of Medicine. doi: 10.1056/nejmp2003762

  3. Lai, C.-C., Liu, Y. H., Wang, C.-Y., Wang, Y.-H., Hsueh, S.-C., Yen, M.-Y., … Hsueh, P.-R. (2020). Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Facts and myths. Journal of Microbiology, Immunology and Infection. doi: 10.1016/j.jmii.2020.02.012

  4. Li, X., Geng, M., Peng, Y., Meng, L., & Lu, S. (2020). Molecular immune pathogenesis and diagnosis of COVID-19. Journal of Pharmaceutical Analysis. doi: 10.1016/j.jpha.2020.03.001

  5. Li, X., Giorgi, E. E., Marichann, M. H., Foley, B., Xiao, C., Kong, X.-P., … Gao, F. (2020). Emergence of SARS-CoV-2 through Recombination and Strong Purifying Selection. doi: 10.1101/2020.03.20.000885

  6. Perlman, S., & Netland, J. (2009). Coronaviruses post-SARS: update on replication and pathogenesis. Nature Reviews Microbiology, 7(6), 439–450. doi: 10.1038/nrmicro2147

  7. Wang, D., Hu, B., Hu, C., Zhu, F., Liu, X., Zhang, J., … Peng, Z. (2020). Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China. Jama, 323(11), 1061. doi: 10.1001/jama.2020.1585

  8. Yan, R., Zhang, Y., Li, Y., Xia, L., Guo, Y., & Zhou, Q. (2020). Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2. Science, 367(6485), 1444–1448. doi: 10.1126/science.abb2762

  9. Zhao, D., Yao, F., Wang, L., Zheng, L., Gao, Y., Ye, J., … Gao, R. (2020). A comparative study on the clinical features of COVID-19 pneumonia to other pneumonias. Clinical Infectious Diseases. doi: 10.1093/cid/ciaa247

  10. Belluck, P. (2020, March 11). What Does the Coronavirus Do to the Body? Retrieved from https://www.nytimes.com/article/coronavirus-body-symptoms.html

  11. Covid-19 | Corona Virus: Epidemiology, Pathophysiology, Diagnostics. (2020). Retrieved from https://www.youtube.com/watch?v=PWzbArPgo-o

  12. Symptoms of Coronavirus. (2020, March 20). Retrieved from https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html

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